All functions |
|
---|---|
Run MAYA for unsupervised pathway acitivity analysis |
|
Run MAYA for unsupervised cell annotation with cell type |
|
Annotate individual cells |
|
Average matrix by column |
|
Extract activity matrix from PCA object |
|
Auxiliary function to determine if a vector is informative. |
|
Generate cell type annotation for each cell and provide complementary results to interpret results |
|
Generate custom color palette |
|
Generate summary of specific pathways and top contributing genes given an annotation |
|
Compute homogeneity table given activity score matrix |
|
Compute Jaccard distance from kNN matrix |
|
Compute Jaccard distance from kNN results |
|
Transform raw count matrix into logCPM matrix |
|
Plots heatmap showing activity scores for each activation mode |
|
Plots heatmap showing individual gene expression of a pathway |
|
Plots heatmap of top contributing genes for each mode |
|
Plots barplot colored by cluster showing distribution of specificity between clusters for each activation mode |
|
Plots UMAP colored by cell annotation |
|
Plots UMAP colored by expression level of a gene |
|
Plots UMAP colored by activity level of a module |
|
Read GMT file |
|
Compute pathway analysis using PCA spotting PCs driven by only one gene. |
|
Run UMAP with fixed seed for reproducibility |
|
Scale matrix rows between 0 and 1 |
|
Compute specificity table given activity score matrix |
|
Build activity matrix and compute UMAP |